Peptide Selection for Targeted Protein Quantitation
نویسندگان
چکیده
منابع مشابه
Control selection for RNA quantitation.
The study of mammalian gene expression is often carried out at the level of mRNA. In such analyses, one usually measures the amount of an mRNA of interest under different conditions such as stress, growth, development, cell and tissue localization or as part of an evaluation of the effects of gene transfection. A variety of techniques exist to measure gene expression and most commonly involve N...
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Quantitative measurement of proteins is one of the most fundamental analytical tasks in a biochemistry laboratory, but widely used immunochemical methods often have limited specificity and high measurement variation. In this review, we discuss applications of multiple-reaction monitoring (MRM) mass spectrometry, which allows sensitive, precise quantitative analyses of peptides and the proteins ...
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ژورنال
عنوان ژورنال: Journal of Proteome Research
سال: 2017
ISSN: 1535-3893,1535-3907
DOI: 10.1021/acs.jproteome.6b00115